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目的讨论卡孕栓在预防剖宫产后出血的应用价值。方法分别选择56例足月孕产妇为观察组和对照组。对照组在胎儿娩出后子宫肌层注射缩宫素10 U,并维持2%静脉滴注;观察组在胎儿分娩断脐后,给予卡孕栓1.0 mg舌下含化,并维持缩宫素2%静脉滴注。统计两组术中、术后出血量和用药前后的血压情况,以及不良反应,评价卡孕栓在预防剖宫产产后出血的运用价值。结果观察组和对照组术中出血量分别为(237±57.8)、(239±58.3)ml,差异无统计学意义(P>0.05)。观察组术后2 h出血量和术后24 h出血量分别为(126±32.2)ml和(57±28.5)ml,与对照组相比,差异有统计学意义(P<0.05)。两组用药前后血压差异无统计学意义(P>0.05)。观察组术后出现恶心3例,呕吐1例,未经特殊处理症状自行消失。两组产后泌乳量差异无统计学意义(P>0.05)。结论使用卡孕栓可以有效预防剖宫产产后出血,值得在临床中推广使用。
Objective To discuss the value of carbamazepine in prevention of bleeding after cesarean section. Methods 56 full-term pregnant women were selected as the observation group and the control group. In the control group, the uterine myometrium was injected with oxytocin 10 U after the fetus was delivered, and 2% intravenous infusion was maintained. After the umbilical cord was separated from the fetus, the observation group was subcongenitated with carbamazepine 1.0 mg and oxytocin 2 % Intravenous infusion. Statistics two groups of intraoperative and postoperative blood loss and blood pressure before and after treatment, as well as adverse reactions to evaluate the use of carbamazepine in the prevention of bleeding after cesarean section. Results The blood loss in observation group and control group were (237 ± 57.8) and (239 ± 58.3) ml, respectively, with no significant difference (P> 0.05). The amount of hemorrhage 2 hours after operation and the amount of hemorrhage 24 hours after operation in the observation group were (126 ± 32.2) ml and (57 ± 28.5) ml, respectively, which were significantly different from those in the control group (P <0.05). No significant difference in blood pressure was found between the two groups before and after treatment (P> 0.05). In the observation group, nausea occurred in 3 cases and vomiting in 1 case, which disappeared without symptoms. There was no significant difference in postpartum lactation volume between the two groups (P> 0.05). Conclusion The use of carbamazepine can effectively prevent cesarean section postpartum hemorrhage, which is worth promoting in clinic.