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目的动态观察老年骨折患者急性脑梗死的发生与C-反应蛋白(CRP)、纤维蛋白原(FBI)水平的相关性。方法 140例神经内科住院脑梗死患者,分为老年骨折后脑梗死组(70例)与非骨折脑梗死组(70例),入院后第2天采集血液,化验C-反应蛋白、纤维蛋白原,对两组上述两项指标进行统计学分析。结果老年骨折后急性脑梗死组C-反应蛋白、纤维蛋白原含量均明显高于非骨折脑梗死组,差异具有统计学意义(P<0.05)。结论 CRP、FBI参与脑梗塞的病理过程,骨折后上述两项指标升高,是老年骨折患者患急性脑梗死的危险因素。检测CRP、FIB可评病情及预后,同时骨科医生可通过检测二者,预防骨折后脑梗死的发生。
Objective To observe the relationship between acute cerebral infarction and C-reactive protein (CRP) and fibrinogen (FBI) in patients with senile fracture. Methods One hundred and fourty patients with neurological inpatients with cerebral infarction were divided into two groups: 70 aged patients with post-fracture cerebral infarction and 70 patients with non-fractured cerebral infarction. Blood samples, C-reactive protein, fibrinogen, Two groups of the above two indicators for statistical analysis. Results The content of C-reactive protein and fibrinogen in elderly patients with acute cerebral infarction after fracture were significantly higher than those in non-fractured cerebral infarction group (P <0.05). Conclusion CRP and FBI are involved in the pathological process of cerebral infarction. The above two indexes are increased after fracture, which are the risk factors for acute cerebral infarction in elderly patients with fracture. Detection of CRP, FIB can be evaluated condition and prognosis, while orthopedic doctors can detect both through the prevention of post-fracture cerebral infarction.