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目的评价环孢素A(Cs A)治疗切脾后复发难治性特发性血小板减少性紫癜(RITP)的疗效。方法对3例Cs A治疗切脾术后复发难治性ITP患者的临床资料进行回顾性分析。结果 Cs A治疗后,3例切脾后复发难治性ITP患者血小板均恢复至正常水平,且无明显副作用。结论环孢素A可以作为脾切除后复发难治性ITP安全、有效的治疗手段之一。
Objective To evaluate the efficacy of cyclosporin A (CsA) in the treatment of recurrent refractory idiopathic thrombocytopenic purpura (RITP) after splenectomy. Methods The clinical data of 3 CsA patients with refractory ITP after splenectomy were retrospectively analyzed. Results After CsA treatment, all three platelets with refractory ITP after splenectomy returned to normal levels with no obvious side effects. Conclusion Cyclosporine A can be used as a safe and effective treatment for recurrent refractory ITP after splenectomy.