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目的:探讨噻托溴铵辅助治疗慢性阻塞性肺疾病的疗效。方法:慢性阻塞性肺疾病患者80例,随机分为治疗组与对照组,各40例。对照组采用常规综合疗法,治疗组在此基础上给予噻托溴铵辅助治疗。结果:治疗后治疗组的FEV1、FEV1/FVC与PEF值明显高于对照组,差异有统计学意义(P<0.05)。对照组出现口干1例,尿潴留1例;治疗组出现口干2例,尿潴留1例。2组不良反应对比差异无统计学意义(P>0.05)。结论:吸入噻托溴铵辅助治疗慢性阻塞性肺病患者能有效改善肺功能,不良反应少,值得临床推广应用。
Objective: To investigate the efficacy of tiotropium in the treatment of chronic obstructive pulmonary disease. Methods: 80 patients with chronic obstructive pulmonary disease were randomly divided into treatment group and control group, 40 cases each. The control group using conventional combination therapy, the treatment group on this basis to give tiotropium adjuvant therapy. Results: After treatment, the FEV1, FEV1 / FVC and PEF of the treatment group were significantly higher than those of the control group, the difference was statistically significant (P <0.05). One case of dry mouth and one case of urinary retention occurred in the control group. Two cases of dry mouth and one case of urinary retention occurred in the treatment group. There was no significant difference in adverse reactions between the two groups (P> 0.05). Conclusion: Inhalation of tiotropium in patients with chronic obstructive pulmonary disease can effectively improve pulmonary function with fewer adverse reactions, which is worthy of clinical application.