论文部分内容阅读
目的探讨脑脊膜血管外皮细胞瘤诊断和治疗。方法回顾分析1984-2005年收治的32例脑脊膜血管外皮瘤,探讨其临床病理特征、临床治疗方法及预后。结果本组男女之比1.4:1;术前仅3例影像学诊断血管外皮瘤,其余均诊断为脑膜瘤。术前影像学误诊率为92%。所有病例均行手术治疗+放射治疗,27例影像学全切,4例次全切除,1例部分切除。获得随访的29例患者1年肿瘤复发率57%,所有病例免疫组化病理结果显示vimentin++。结论脑脊膜的血管外皮瘤为起源于脑脊膜问叶组织、低度恶性的肿瘤,男性多见,术前易与脑膜瘤相混淆,免疫组化病理有特征性表现;该肿瘤易复发,手术力争全切是改善预后的最重要因素;不管术中是否全切肿瘤,术后都应辅助放射治疗以改善预后。
Objective To investigate the diagnosis and treatment of cerebrospinal fluid hemangiopericytoma. Methods Retrospective analysis of 32 cases of cerebrospinal fluid hemangiopericytoma treated from 1984 to 2005, to explore its clinical and pathological features, clinical treatment and prognosis. Results The ratio of men and women in this group was 1.4: 1. Only 3 cases of vascular hemangiomas were diagnosed before operation, and the others were diagnosed as meningioma. Misdiagnosis rate of preoperative imaging was 92%. All cases were treated with surgery + radiotherapy, 27 cases of imaging resection, subtotal resection in 4 cases, partial resection in 1 case. The follow-up of 29 patients 1 year tumor recurrence rate of 57%, all cases of immunohistochemical results showed that vimentin ++. Conclusions The hemangiopericytoma of cerebrospinal meningioma is a low-grade malignant tumor originated from the meningococcal meningioma. It is common in males and is easily confused with meningioma before operation. The immunohistochemistry has the characteristic features. Surgical strive to cut all is the most important factor in improving prognosis; regardless of whether the operation of the whole tumor, postoperative radiotherapy should be assisted to improve the prognosis.