异烟肼片剂的质量考察

• 作 者: 吴锦健 董志远 昌卓娅
• 机 构: 新疆医学院药学系药剂学教研室,冶建职工医院,自治区中医院,
• 出 处: 新疆医学院学报
• 发表日期: 1986年02期
• 关键词: 片剂 异烟肼 体外溶出度 定仪 差异情况 药品质量 质量考察 溶出速度 药物制剂 溶出度

异烟肼片剂是属于生物有效度有问题的药物制剂之一,在生产上应当加以控制其药物的溶出速度。因此对围内四个药厂的四个批号的异烟肼片剂做了体外溶出度的测定,观察其差异情况。从而考察异烟肼片剂质量,为控制和提高药品质量、改进生产工艺提供依据。一、仪器 78 X-2型片剂四用测定仪(上海黄海制药厂);

Isoniazid tablets are one of the bioavailability problems of pharmaceutical preparations, should be controlled in the production of its drug dissolution rate. Therefore, the four pharmaceutical companies around the four batch of isoniazid tablets in vitro dissolution was measured to observe the differences. In order to investigate the quality of isoniazid tablets, in order to control and improve the quality of medicines, to provide a basis for improving the production process. First, the instrument 78 X-2 tablet with four detector (Shanghai Huanghai Pharmaceutical Factory);