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目的:探讨经直肠超声引导前列腺系统穿刺活检术诊断前列腺癌的临床价值。方法:对238例行经直肠超声引导前列腺系统穿刺活检术患者的资料进行回顾性分析。结果:检出前列腺癌患者59例,临床分期T1期:0例,T2期:8例,T3期:22例,T4期:29例。穿刺阳性者血清总前列腺特异性抗原(t-PSA)水平、前列腺体积、PSA密度(PSAD)、(f/t)/PSAD、前列腺钙化率分别为82.5(2.6～490.5)ng/ml、47.6(17.2～110.6)cm3、2.5(0.05～22.0)ng.ml-1.cm-3、0.381(0.008～1.71)、33.9%,穿刺阴性者分别为12.5(0.97～54.4)ng/ml、70.1(12.3～206.6)cm3、0.23(0.01～2.39)ng.ml-1.cm-3、1.685(0.071～9.938)、4.1%,两组有统计学差异。238例患者均未发生严重并发症。结论:经直肠超声引导前列腺系统穿刺活检术易操作,前列腺癌检出率较高,必要时进一步分析PSAD、(f/t)/PSAD值可提高穿刺特异性,严重并发症少,目前仍是诊断前列腺癌的主要方法。
Objective: To investigate the clinical value of transrectal ultrasound guided prostatic biopsy in the diagnosis of prostate cancer. Methods: A retrospective analysis was performed on 238 patients undergoing transrectal ultrasound guided prostatic biopsy. Results: 59 cases of prostate cancer were detected. There were 0 cases in clinical stage T1, 8 cases in T2 stage, 22 cases in T3 stage and 29 cases in T4 stage. Prostate volume, PSA density (PSAD), (f / t) / PSAD, and prostate calcification rates were 82.5 (2.6-490.5) ng / ml and 47.6 17.2-110.6) cm3,2.5 (0.05-22.0) ng.ml-1.cm-3,0.381 (0.008-1.71), 33.9% respectively, and the puncture negative values were 12.5 (0.97-54.4) ng / ml, 70.1 ~ 206.6) cm3,0.23 (0.01-2.39) ng.ml-1.cm-3,1.685 (0.071-9.938), 4.1%, there was a significant difference between the two groups. No serious complications occurred in 238 patients. CONCLUSIONS: Prostate cancer is easily diagnosed by transrectal ultrasound guided prostatic biopsy and has a high detection rate of prostate cancer. Further analysis of PSAD (f / t) / PSAD values may improve the specificity of the puncture if necessary, with few serious complications and is still The main method of diagnosing prostate cancer.