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目的探讨引发短暂性脑缺血发作(TIA)发展为脑梗死的相关危险因素。方法选取2013年1月至2015年1月深圳市人民医院收治的160例TIA患者作为研究对象,根据其住院期间是否发展为脑梗死分为梗死组(38例)和非梗死组(122例),统计两组患者年龄、性别、既往病史、入院时血压、吸烟饮酒情况、TIA次数、症状持续时间及低密度脂蛋白胆固醇(LDL-C)、C-反应蛋白(CRP)、D-二聚体水平。结果单因素分析结果显示,年龄、冠状动脉粥样硬化性心脏病(CHD)、糖尿病史、高血压、TIA次数≥3次、症状持续时间≥1 h及LDL-C、CRP、D-二聚体水平均为TIA发展为脑梗死的危险因素。结论年龄、CHD、糖尿病与高血压史,TIA次数与发作持续时间,CRP、D-二聚体和LDL水平均为TIA发展为脑梗死的危险因素。
Objective To explore the related risk factors of developing transient ischemic attack (TIA) into cerebral infarction. Methods A total of 160 TIA patients admitted to Shenzhen People’s Hospital from January 2013 to January 2015 were enrolled in the study. According to whether they developed cerebral infarction during hospitalization, they were divided into three groups: infarction group (n = 38) and non-infarction group (n = 122) , The age, gender, past medical history, blood pressure, smoking and drinking, the number of TIA, the duration of symptoms and the levels of LDL-C, C-reactive protein (CRP) Body level. Results The results of univariate analysis showed that age, coronary heart disease (CHD), history of diabetes, hypertension, TIA ≥ 3 times, duration of symptoms ≥ 1 h and LDL-C, CRP, D-dimer Body volume is a risk factor for the development of TIA for cerebral infarction. Conclusions Age, CHD, history of diabetes mellitus and hypertension, number of TIA and duration of attack, CRP, D-dimer and LDL are the risk factors for TIA to develop cerebral infarction.