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目的 探讨 期子宫内膜癌临床特征及预后相关因素。方法 回顾性分析我院 1986年 1月～ 1998年 12月间收治的 2 8例 期子宫内膜癌患者临床病理资料和随访结果。结果 12 8例患者中 a期 13例( 46 .4% ) , b期 3例 ( 10 .7% ) , c期 12例 ( 42 .9% ) ;子宫内膜样腺癌 2 0例 ( 71.4% ) ,腺鳞癌 4例 ( 14.3% ) ,浆乳癌 3例 ( 10 .7% ) ,透明细胞癌 1例 ( 3.6 % ) ;2 8例中 ,病理分级 1、2和 3级分别为 11、9和 8例 ;2随访 6～ 10 8个月 ,复发转移 13例 ( 46 .4% ) ,死亡 10例 ( 35 .7% ) ,五年生存率为 41.6 % ;3子宫外多处病灶 12例 ,复发转移 8例 ,术后辅助化疗 16例 ,复发转移 7例。结论 期子宫内膜癌预后较差 ,子宫浆膜受侵、子宫外多处癌灶、宫旁组织受侵犯、宫旁淋巴管或血管有癌栓及淋巴结癌转移仍是影响 期子宫内膜癌预后的重要因素。死亡原因多为盆腹腔复发和远处转移。术后辅助化疗对五年生存率无明显影响。
Objective To investigate the clinical characteristics and prognosis of endometrial cancer related factors. Methods The clinical and pathological data and the follow-up results of 28 patients with endometrial cancer treated in our hospital from January 1986 to December 1998 were retrospectively analyzed. Results A total of 12 patients (13 cases (46.4%) in stage a, 3 cases (10.3%) in stage b, 12 cases (42.9%) in stage c and 20 cases (71.4 ), Adenosquamous carcinoma in 4 cases (14.3%), breast cancer in 3 cases (10.7%) and clear cell carcinoma in 1 case (3.6%). In 28 cases, pathological grade 1, 2 and 3 were 11 , 9 and 8 cases, respectively. 2 Followed up for 6-10 months, 13 cases (46.4%) had recurrence and metastasis, 10 (35.7%) died, and the 5-year survival rate was 41.6% 12 cases, recurrence and metastasis in 8 cases, postoperative adjuvant chemotherapy in 16 cases, recurrence and metastasis in 7 cases. Conclusions The prognosis of endometrial cancer is poor, uterine invasion of the serosa, multiple extra-uterine lesions, uterine tissue invasion, uterine lymphatic vessels or blood vessels with thrombus and lymph node metastasis is still affected endometrial cancer Important prognostic factors. Reasons for death were pelvic abdominal recurrence and distant metastasis. Postoperative adjuvant chemotherapy had no significant effect on the five-year survival rate.