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目的:探讨硝普钠联合多巴胺治疗难治性心功能不全的临床效果。方法:以本院住院治疗的难治性心功能不全患者70例为研究对象,患者收治时间为2013年2月-2015年1月,随机将其分为对照组和观察组,观察组以硝普钠联合多巴胺作为治疗方案,与对照组临床常规治疗方案比较,分析临床药物治疗效果。结果:观察组有效率为94.3%;对照组有效率为54.3%,组间比较,差异具有统计学意义(P<0.01)。两组患者治疗后的左室射血分数、心室率及脑利钠前体水平均较治疗前显著改善(P<0.05)。而在治疗后两组的上述指标比较,差异无统计学意义(P>0.05)。结论:硝普钠联合多巴胺治疗难治性心功能不全与临床常规疗法比较,疗效显著,左室射血分数、心室率及脑利钠前体水平均较治疗前显著改善。
Objective: To investigate the clinical effects of sodium nitroprusside combined with dopamine in the treatment of refractory cardiac insufficiency. Methods: Seventy patients with refractory cardiac insufficiency hospitalized in our hospital were studied. The patients were treated from February 2013 to January 2015 and randomly divided into control group and observation group, Sodium combined with dopamine as a treatment regimen, compared with the control group clinical routine treatment programs, analysis of clinical drug treatment. Results: The effective rate was 94.3% in the observation group and 54.3% in the control group. The difference between the two groups was statistically significant (P <0.01). Left ventricular ejection fraction, ventricular rate and brain natriuretic peptide level were significantly improved in both groups after treatment (P <0.05). In the two groups after treatment, the above indicators, the difference was not statistically significant (P> 0.05). Conclusion: Sodium nitroprusside combined with dopamine treatment of refractory cardiac insufficiency compared with clinical conventional therapy, the effect is significant, left ventricular ejection fraction, ventricular rate and brain natriuretic peptide levels were significantly improved than before treatment.