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前列腺癌是男性泌尿生殖道最常见的肿瘤,它常转移至骨骼如骨盆、肋骨、脊柱等,但转移至眼眶罕见。Henderson(1973)复习Mayo 医院1948～1966年眼眶转移瘤病例,未见一例前列腺癌眼眶转移。1975年Font 和Ferry 复习227例眼和眼眶转移癌病例,仅一例前列腺癌眼眶转移。本文作者报告一例70岁患者,4年前已确诊为前列腺癌腰椎转移,经放疗症状缓解。6周前出现左眼突出,眼睑张开困难,眼球运动障碍,视力丧失伴疼痛。头颅平片见左侧蝶骨大翼骨硬化。CT 扫描示左眶尖、中颅凹,颞窝侧壁见一软组织块影。同位素骨扫描见左侧蝶骨、颞骨同位紊局限性聚集。血清前列腺酸性磷酸醣酶升高达28.5ng/ml(正常为0～3ng/ml)。患者作直线加速器治疗,6周后左眼突出消退,眼球活动自如,视力部分恢复,左颞窝外观正常。作者认为手术切除眼眶转移灶不是指征,甚至眼眶为唯一的转移灶。主张作放疗,目的是
Prostate cancer is the most common tumor of the male genitourinary tract. It often metastasizes to bones such as pelvis, ribs, spine, etc., but is rarely seen in the eyelids. Henderson (1973) reviewed cases of orbital metastases in the Mayo Hospital from 1948 to 1966. There was no case of metastatic prostate cancer. In 1975, Font and Ferry reviewed 227 cases of metastatic eye and eyelid cancer, and only one case of metastatic prostate cancer. The authors report a case of a 70-year-old patient who had been diagnosed with lumbar metastases of prostate cancer four years ago and had their symptoms resolved by radiotherapy. 6 weeks before the emergence of left eye, eyelid opening difficulties, eye movement disorders, vision loss with pain. Skull flat sheet see left sphenoid fin-bone sclerosis. The CT scan showed the left iliac crest and the middle cranial fossa, and a soft tissue block shadow appeared in the lateral wall of the axillary fossa. Isotope bone scans are shown on the left side of the sphenoid bone and the ischemic osseointegration. Serum prostate acid phospholyase was elevated up to 28.5 ng/ml (normally 0-3 ng/ml). The patient was treated with a linear accelerator. After 6 weeks, the left eye was retracted, the eyeball moved freely, the visual acuity was partially recovered, and the left axillary fossa was normal in appearance. The authors believe that surgical removal of the eyelid metastases is not an indication, and even the eyelid is the only metastasis. Claims for radiotherapy, the purpose is