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目的对抗-CCP抗体与RF于类风湿关节炎的诊断价值进行研究及判定。方法选取该院2016年2月—2017年1月收治的类风湿关节炎患者作为A组,另选取同期的非类风湿关节炎患者作为B组,健康志愿者为C组,3组体检人员各30例,并将3组体检人员的血清中抗-CCP抗体及RF进行对比。结果 A组类风湿关节炎患者的血清-CCP抗体浓度为(21.55±10.63)RU/mL,血清中RF浓度为(58.02±22.35)U/mL,均较B、C组差异有统计学意义,且血清中抗-CCP抗体、血清RF阳性率分别为66.67%及83.33%,均高于B、C_2组(P<0.05)。结论抗-CCP抗体与RF对类风湿关节炎的诊断价值显著,具有较高的阳性率,可为临床中类风湿关节炎的确诊提供有力依据。
Objective To evaluate the diagnostic value of anti-CCP antibody and RF in rheumatoid arthritis. Methods The patients with rheumatoid arthritis who were admitted from February 2016 to January 2017 in the hospital were selected as group A, and the non-rheumatoid arthritis patients were selected as group B in the same period. The healthy volunteers were in group C and the three groups of medical staff 30 cases, and the three groups of sera from the anti-CCP antibody and RF were compared. Results The serum concentration of -CCP antibody in group A was (21.55 ± 10.63) RU / mL and the concentration of serum RF in serum was (58.02 ± 22.35) U / mL, which was significantly different from that of group B and C, The positive rates of anti-CCP antibody and serum RF in serum were 66.67% and 83.33% respectively, which were higher than those in B and C_2 groups (P <0.05). Conclusion The anti-CCP antibody and RF have significant diagnostic value on rheumatoid arthritis and have a high positive rate, which can provide a valid basis for the diagnosis of rheumatoid arthritis in clinic.