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目的观察雾化吸入干扰素治疗重型毛细支气管炎临床效果。方法 26例重型毛细支气管炎住院的婴幼儿,将其随机分为对照组和治疗组,各13例。两组均给予综合治疗,治疗组在此基础上加干扰素雾化吸入治疗,观察两组的疗效。结果治疗组治疗3、5 d症状体征评分和住院时间均明显优于对照组,差异均有统计学意义(P<0.05)。结论干扰素雾化吸入治疗重型毛细管炎在临床能够更快缓解患儿的临床症状体征,缩短患儿住院时间,疗效明显,而且没有明显不良反应,家长患儿易于接受,值得在临床上推广。
Objective To observe the clinical effect of inhaled interferon on severe bronchiolitis. Methods Twenty - six infants and young children with severe bronchiolitis were randomly divided into control group and treatment group, with 13 cases in each group. Both groups were given comprehensive treatment, the treatment group on this basis plus interferon inhalation therapy, the efficacy of the two groups were observed. Results The symptom score and hospital stay of the treatment group were significantly better than those of the control group on the 3rd and 5th day after treatment (P <0.05). Conclusions Interferon atomization inhalation for treatment of severe acute cholangitis in the clinic can relieve clinical symptoms and signs of children more quickly, shorten the hospitalization time of patients with obvious curative effect, and no obvious adverse reactions. Parents and children are easy to accept and should be popularized clinically.