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目的：观察腹腔内注入顺磁性造影剂维影钆胺（Ｇｄ－ＤＴＰＡ）后大鼠脑胶质瘤的显示和强化情况。方法：８０只ＳＤ大鼠脑内胶质瘤细胞种植后分成两组，分别经静脉内和腹腔内注入造影剂后行磁共振扫描。结果：经腹腔内注入造影剂与经静脉内注入造影剂两种方法对肿瘤的显示和强化相差不显著。结论：ＳＤ大鼠脑胶质瘤磁共振造影剂Ｇｄ－ＤＴＰＡ的给药途径可选用经腹腔内注入，其合适浓度为０．１～０．５ｍｍｏｌ／ｋｇ。
OBJECTIVE: To observe the expression and enhancement of rat glioma after intraperitoneal injection of paramagnetic gadolinium (Gd-DTPA). Methods: Eighty SD rat brain glioma cells were divided into two groups. The rats were injected with contrast agent intravenously and intraperitoneally respectively and then scanned by MRI. Results: There was no significant difference between the two methods of intracavitary injection of contrast agent and intravenous injection of contrast medium on the display and enhancement of tumor. Conclusion: Gd-DTPA can be injected intraperitoneally in SD rat glioma magnetic resonance imaging contrast agent, and its suitable concentration is 0.1 ~ 0.5mmol / kg.