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本文对171例佝偻病患儿的免疫状态进行了观察,并与健康小儿对照。结果:佝偻病组的 PHA 红斑和 OT硬结均小于正常组(P<0.01);E 玫瑰花结形成率低于正常组(P<0.05);且有年龄越小受抑越甚之趋势。IgG、IgM、IgA 和补体 C_3差别无统计学意义。PHA受抑程度与病期有关,在佝偻病不同年龄组、不同碱性磷酸酶组、贫血与不贫血组、活动期及稳定期组间,差别均显著。因此认为,PHA 皮试是临床测定细胞免疫功能的一种有效方法。
In this paper, 171 cases of rickets in children with immune status were observed, and healthy children control. Results: The erythroderma of PHA and OT in patients with rickets were significantly lower than those in the normal group (P <0.01). The formation rate of rosette was lower than that of the normal group (P <0.05). IgG, IgM, IgA and complement C_3 difference was not statistically significant. The degree of inhibition of PHA was related to the stage of disease. There was significant difference between the different age groups of rickets, different alkaline phosphatase groups, anemia and non-anemia group, active and stable groups. Therefore, PHA skin test is an effective method for clinical determination of cellular immune function.