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为探讨铝氟联合作用时铁与矿物代谢的关系 ,在鸡铝氟病及铝危害模型基础上对全血铁和骨铁用AAS法进行了检测。结果表明 ,性成熟前各实验组全血铁均升高 ,但以加氟组更为明显 ;性成熟后饲料加入氟化物的 3个组全血铁仍高于对照 ,未加的另 3个组则低于或接近对照组。骨铁含量均有所下降。饲氟、骨氟、骨铝与全血铁有明显正相关 (P <0 2 )或显著正相关 (P <0 0 5) ,与骨铁有明显负相关 ,差异均有显著或非常明显 (P <0 1)意义。全血铁与全血钙、镁、磷 ,骨灰化率、骨矿含量、平均骨壁厚度、骨矿沉积率均呈显著正相关。骨铁与骨钙、镁呈显著或明显负相关 ,与成骨细胞指数、破骨细胞指数、类骨质体积呈明显或非常显著(P <0 0 1)负相关 ,与骨单位吸收周期呈明显正相关。全血铁与骨铁呈明显负相关。提示 ,全血与骨骼铁代谢是能分离又相对应的体系 ,可能有相互平衡、调节和补偿作用。铁不仅是血红蛋白的必需成分 ,还与骨矿化和骨细胞及矿物元素有密切关系。
In order to investigate the relationship between iron and mineral metabolism during the joint action of aluminum and fluoride, AAS was performed on whole blood iron and skeletal iron on the basis of chicken aluminum fluoride disease and aluminum hazard model. The results showed that before the sexual maturity in all experimental groups were elevated in all iron, but fluoride group was more obvious; sexual maturity fluoride feed after the three groups were still higher than the control of total iron, the other three Group was lower than or close to the control group. Bone iron content decreased. There was a significant positive correlation (P <0 2) or significant positive correlation (P 0 05) with fluoride, bone fluoride, bone aluminum and whole blood iron, and significant negative correlation with bone iron P <0 1) meaning. Whole blood iron and calcium in whole blood, magnesium, phosphorus, rate of ascites, bone mineral content, average bone wall thickness, bone mineral deposition rate was significantly positively correlated. There was a significant or significant negative correlation between bone iron and bone calcium and magnesium, negatively correlated with osteoblast index, osteoclast index and osteoid volume (P <0.01), and bone mineral absorption cycle Obviously positive correlation. Complete blood iron and bone iron was significantly negatively correlated. Tip, whole blood and bone iron metabolism can separate and correspond to the system, may have mutual balance, regulation and compensation role. Iron is not only an essential component of hemoglobin, but also with bone mineralization and bone cells and mineral elements are closely related.