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本研究比较了准分子激光,连续及脉冲YAG激光声光调Q倍频YAG激光和钬铒铥(αβ-YLF)激光照射人尸体主动脉及其斑块的作用。结果表明:五种激光均可汽化主动脉壁(包括正常及斑块),汽化凹坑深度随激光能量的增加而加深。在相同激光能量下,汽化斑块的凹坑深度大于汽化主动脉壁的凹坑深度。其中,声光调Q倍频YAG激光,αβ-YLF激光穿透力较差,而准分子激光,连续及脉冲YAG激光穿透力较强。形态学观察发现,连续YAG激光汽化组织产生凹坑边缘不整齐,伴有明显热损伤。αβ-YLF激光次之,而准分子激光汽化凹坑边缘整齐,几乎不伴热损伤。准分子激光有可能成为激光血管成形术的较理想的激光源。
This study compared the effects of excimer laser, continuous and pulsed YAG laser acousto-optic Q-switched QAG YAG laser and holmium erbium 铥 (αβ-YLF) laser on human cadaver aorta and its plaque. The results show that all five kinds of laser can vaporize the aortic wall (including normal and plaque), and the depth of vaporization pit deepens with the increase of laser energy. Under the same laser energy, the depth of the pits of the vaporized plaques is greater than the depth of the pits of the wall of the vaporized aorta. Among them, acousto-optic Q-switched QAG YAG laser has poor penetration of αβ-YLF laser, while excimer laser, continuous and pulsed YAG laser have stronger penetrating power. Morphological observation found that continuous YAG laser vaporization tissue generated pits uneven edge, accompanied by significant thermal damage. αβ-YLF laser followed by excimer laser vaporization dimple edge neat, almost no thermal damage. Excimer lasers are likely to be the ideal laser source for laser angioplasty.