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1961年Moore和Canier首次报告南美洲出现恶性疟原虫对氯喹敏感性减低现象,以后Contacos等报告东南亚地区存在抗氯喹的恶性疟原虫,1973年我组发现云南省勐定地区恶性疟原虫对氯喹产生抗药性,随后进一步在德宏州昔马、畹町,西双版纳州勐棒等地进行调查,均证实有抗氯喹恶性疟原虫存在。抗氯喹恶性疟原虫分布面广,在疟疾防治工作中须引起足够重视。现
1961 Moore and Canier for the first time in South America, Plasmodium falciparum chloroquine susceptibility decreased phenomenon, after Contacos and other reports of the presence of chloroquine-resistant Plasmodium falciparum in Southeast Asia, 1973 I found in Yunnan Mengding Plasmodium falciparum chloroquine production Resistance, then further in Dehong Zhouma, Wanding, Xishuangbanna Meng stick and other places were investigated, all confirmed the presence of anti-chloroquine Plasmodium falciparum. Resistant to chloroquine Plasmodium falciparum widespread, malaria prevention and control must be given due attention. Now