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目的比较2005年和2012年心内科住院患者的血脂水平,为血脂异常的防治提供依据。方法采用横断面研究,回顾性查阅2005年和2012年中山大学附属第三医院心内科住院患者1 647例的病历,收集患者的一般情况、血脂水平、疾病诊断等资料。将患者按年龄分为4组(分别为≤44岁、45~59岁、60~74岁、≥75岁),按患病情况分为3组(分别为单纯高血压病组、冠心病及其等危症组、其他心血管病组),用SPSS 13.0软件进行统计学分析比较。结果与2005年比较,2012年住院患者的血脂异常检出率、高胆固醇(TC)血症、高低密度脂蛋白胆固醇(LDL-C)血症检出率均明显降低(均P<0.001)。两年的低高密度脂蛋白胆固醇(HDL-C)检出率均为45%。2005年女性患者的TC、LDL-C水平高于男性(P<0.001,P=0.020),2012年女性患者的TC、LDL-C、HDL-C水平高于男性(P<0.01)。2005年和2012年44岁以下患者TC、LDL-C水平最低,45~59岁组的TG水平高于其他3组。2005年单纯高血压组TG水平高于冠心病及其等危症组(P<0.05),2012年单纯高血压病组的TC、HDL-C、LDL-C水平高于冠心病及其等危症组(P<0.05)。结论与2005年比较,2012年心内科住院患者的血脂水平趋于优化,但患者血脂异常检出率仍较高,女性患者血脂水平高于男性患者,单纯高血压患者血脂水平高于其他心血管病患病人群,作为心血管病的高危因素之一,血脂异常的防控仍然是慢性病管治的一个重要环节。
Objective To compare the blood lipid levels of inpatients with cardiology in 2005 and 2012 and provide evidence for the prevention and treatment of dyslipidemia. Methods The clinical data of 1 647 inpatients admitted to Department of Cardiology of the Third Affiliated Hospital of Sun Yat-sen University from 2005 to 2012 were retrospectively reviewed. The general conditions, blood lipid level and diagnosis of the disease were collected. The patients were divided into 4 groups according to their age (≤44, 45-59, 60-74, and ≥75 years old). The patients were divided into three groups according to the prevalence: hypertension group, coronary heart disease and Its equal risk group, other cardiovascular disease group), using SPSS 13.0 software for statistical analysis and comparison. Results Compared with 2005, the detection rate of dyslipidemia, hypercholesterolemia and high and low density lipoprotein cholesterol (LDL-C) in hospitalized patients in 2012 were significantly lower (all P <0.001) . Two-year low-density lipoprotein cholesterol (HDL-C) detection rate was 45%. The levels of TC and LDL-C in female patients in 2005 were higher than those in men (P <0.001, P = 0.020). The levels of TC, LDL-C and HDL-C in female patients in 2012 were higher than those in men (P <0.01). The levels of TC and LDL-C were the lowest in patients under 44 years of age in 2005 and 2012, and the levels of TG in 45- 59 age group were higher than those in other three groups. In 2005, the level of TG in hypertensive group was higher than that in CHD group (P <0.05). The levels of TC, HDL-C and LDL-C in patients with essential hypertension in 2012 were higher than those in CHD patients Disease group (P <0.05). Conclusion Compared with 2005, the blood lipid levels of inpatients in the Department of Cardiology in 2012 tend to be optimized, but the detection rate of dyslipidemia is still high, the blood lipid level of female patients is higher than that of male patients, the blood lipid level of patients with hypertension is higher than that of other cardiovascular Patient population, as one of the risk factors of cardiovascular disease, prevention and control of dyslipidemia is still an important part of chronic disease management.