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１３１Ⅰ标记的人血清低密度脂蛋白（ＬＤＬ）与羊抗人ＡｐｏＢ抗体形成的ＬＤＬ－抗体复合物以及１３１Ⅰ－ＬＤＬ，进行由静脉注入正常家兔体内和小鼠腹腔巨噬细胞培养两项实验。结果显示，抗ＡｐｏＢ抗体的加入加快了ＬＤＬ在家兔血浆中的清除率；增加了网状内皮系统（如肝、脾组织）和巨噬细胞对ＬＤＬ的摄取；２４ｈ细胞培养可见巨噬细胞内有大量脂滴堆积。结果表明，抗ＡｐｏＢ抗体增加组织和巨噬细胞对ＬＤＬ的大量摄取，这可能在动脉粥样硬化形成中起重要作用。
131I-labeled human serum LDL and goat anti-human ApoB antibody and 131I-LDL, two experiments were conducted by intravenous injection into normal rabbits and mouse peritoneal macrophages. The results showed that the addition of anti-ApoB antibody accelerated the clearance rate of LDL in rabbits plasma; increased the uptake of LDL by reticuloendothelial system (such as liver and spleen) and macrophages; 24h cell culture showed macrophage There is a lot of lipid droplets accumulation. The results indicate that anti-ApoB antibodies increase the uptake of LDL by tissues and macrophages, which may play an important role in the development of atherosclerosis.