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恶性组织细胞病(Malignant Histiocytosis,简称恶组)是一种单核-吞噬细胞系统中的组织细胞恶性增生的疾病。临床表现主要为发热、消瘦、贫血、迅速衰竭、淋巴结及肝脾肿大,终末期常出现黄疸、紫癜以及白细胞和血小板减少。病程发展急剧,预后恶劣,病人往往在半年内死亡。此病在我国尤为多见,已报道的成人与小儿病例有千余例,国外截至1978年报告近200例,亦不象过去认为的那
Malignant Histiocytosis (Malignant Histiocytosis) is a disease of malignant proliferation of tissue cells in the mononuclear-phagocyte system. The main clinical manifestations of fever, weight loss, anemia, rapid failure, lymph nodes and hepatosplenomegaly, often terminal jaundice, purpura and white blood cells and thrombocytopenia. Rapid course of disease development, poor prognosis, patients often die within six months. The disease is especially prevalent in our country. More than a thousand cases have been reported in adult and pediatric cases. Nearly 200 cases were reported abroad as of 1978,