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目的:分析输尿管镜钬激光碎石术后全身炎性反应综合征(SIRS)发生的危险因素,寻找更加有效和安全的输尿管镜手术途径。方法:回顾性分析输尿管镜下钬激光碎石术294例,分别对输尿管镜手术时间、术前有无尿路感染、结石负荷、双侧结石或单侧结石、性别和年龄等因素与SIRS发生的关系进行比较分析。结果:术前有尿路感染及结石负荷较大的患者术后SIRS发生率明显增高,而手术时间、性别、年龄等因素对SIRS发生率无显著影响。结论:由于手术途径及结石的客观因素,输尿管钬激光碎石术有发生SIRS的可能,术前充分准备,术中规范操作及低压灌注,术后早期诊断治疗是降低手术SIRS的有效措施和途径。
Objective: To analyze the risk factors of systemic inflammatory response syndrome (SIRS) after ureteroscopic holmium laser lithotripsy and to find a more effective and safe ureteroscopic surgical approach. Methods: A retrospective analysis of 294 cases of ureteroscopic holmium laser lithotripsy were performed with ureteroscopic surgery time, preoperative urinary tract infection, stone load, bilateral stone or unilateral calculi, gender and age, and SIRS The relationship between the comparative analysis. Results: The incidence of SIRS was significantly increased in patients with preoperative urinary tract infection and stones load, but the operation time, sex, age and other factors had no significant effect on the incidence of SIRS. Conclusion: Because of the objective factors of operation and calculi, the ureteral holmium laser lithotripsy may have the possibility of SIRS, preoperative preparation, intraoperative standard operation and low pressure perfusion, early postoperative diagnosis and treatment are effective measures and ways to reduce the surgical SIRS .