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目的:分析总结鼻腔胸膜外孤立性纤维瘤(EPSFT)的临床表现,影像学征象,病理特征,治疗及预后,以提高对鼻腔EPSFT的诊治水平。方法:报告2例EPSFT患者的住院病例资料,分析其临床症状,影像特征,血常规生化指标,治疗方法,光镜病理,免疫组织化学特点和随访结果。结果:①鼻腔EPSFT以鼻塞、鼻出血为主要临床症状。②鼻腔EPSFT的放射影像学表现与鼻腔肿瘤无特征性区别,增强扫描均有增强表现,与鼻腔血管瘤有相似之处。③鼻腔EPSFT患者血常规与生化检查无特异性改变。④鼻腔EPSFT确诊依赖病理学检查及免疫组织化学特征。⑤2例患者均接受手术治疗,彻底切除肿瘤。1例随访2年,1例随访1年,均无复发。结论:建议术前行DSA检查与血管栓塞,手术完整切除肿瘤是首选的、惟一疗效确切的治疗方法,预后一般较好。
OBJECTIVE: To analyze and summarize the clinical manifestations, imaging features, pathological features, treatment and prognosis of nasopharynx extranodal solitary fibroma (EPSFT) in order to improve the diagnosis and treatment of nasal EPSFT. Methods: Two cases of inpatients with EPSFT were reported and their clinical symptoms, imaging features, blood biochemical parameters, treatment methods, light microscopic pathology, immunohistochemical features and follow-up results were analyzed. Results: nasal EPSFT with nasal congestion and nose bleeding as the main clinical symptoms. Nasopharyngeal EPSFT radiological findings and no distinctive features of nasal tumors, enhanced scanning have enhanced performance, and nasal hemangiomas have similarities. ③ nasopharyngeal EPSFT blood tests and biochemical tests without specific changes. ④ Nasopharyngeal EPSFT diagnosis depends on pathological examination and immunohistochemical features. ⑤ 2 patients underwent surgical treatment, complete removal of the tumor. One case was followed up for 2 years and one case was followed up for 1 year. No recurrence occurred. Conclusion: It is recommended that DSA and vascular embolism be performed preoperatively. Complete resection of the tumor by surgery is the first choice. The only effective treatment is DSA. The prognosis is generally good.