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患者男性,58岁,79年4月4日以“坐骨神经炎”住院治疗。入院后给予消炎痛25毫克、维生素B_120毫克口服,每日三次;肌注维生素B_(12)100微克,每日一次。连续用药三日,未见不良反应。于4月7日为提高疗效而加大维生素B_(12)用量至200微克,肌注后约5分钟,患者自觉头晕、恶心、胸闷不适、呼吸困难、出冷汗,随即不省人事,烦躁不安,口唇发绀,小便失禁,脉搏细速,血压骤降。当即使病人平卧,皮下注射肾上腺素1毫克,肌注异丙嗪25毫克、氟美松10毫克、654—Ⅱ20毫克,静注50%萄葡糖60毫升,同时鼻管吸
Male patient, 58 years old, April 4, 1979 with “sciatic neuritis” hospitalized. After admission given indomethacin 25 mg, vitamin B_120 mg orally three times a day; intramuscular injection of vitamin B_ (12) 100 micrograms, once daily. Continuous medication for three days, no adverse reactions. On April 7 to increase the efficacy of vitamin B_ (12) to 200 micrograms, about 5 minutes after intramuscular injection, the patient consciously dizzy, nausea, chest tightness, discomfort, dyspnea, a cold sweat, then unconscious, restless , Cyanotic lips, urinary incontinence, pulse fine speed, sudden drop in blood pressure. Even when the patient supine, subcutaneous injection of 1 mg of epinephrine, intramuscular injection of 25 mg of promethazine, dexamethasone 10 mg, 654-Ⅱ 20 mg intravenous injection of 50% glucose 60 ml, while nasal suction tube