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选４０只体重在８０～１２０ｇＳＤ健康雄性大鼠，随机分为５组。分别喂以不同铁（ＦｅＳＯ４）、锌（ＺｎＳＯ４）含量的饲料。第１组：Ｆｅ：２０μｇ／ｇ，Ｚｎ：１８μｇ／ｇ；第２、３、４组Ｆｅ分别为：４０、８０、１６０μｇ／ｇ，Ｚｎ均为１８μｇ／ｇ；第５组Ｆｅ４０μｇ／ｇ，Ｚｎ３６μｇ／ｇ。喂养２０ｄ后按体重５．５５×１０－２ＧＢｑ／ｇ进行６５Ｚｎ灌胃，当日起连续收集５ｄ粪尿，用６５Ｚｎ示踪法测定各组动物锌吸收、存留与体内分布情况。结果表明：第１、２、３、４组间大鼠锌吸收率、存留率、体内分布无显著性差异，低锌组（１、２、３、４组）大鼠体内的锌吸收率与存留明显高于高锌组（５组），１组与５组之间的锌体内分布也有显著差异。说明在本次实验条件下，非血红素铁对无机锌在大鼠体内吸收与存留影响不大，而饲料中锌含量增加可显著抑制锌的吸收率与存留率，其影响作用比铁的作用显著
Forty healthy male rats weighing 80-120g were randomly divided into five groups. Feeds were fed with different iron (FeSO4), zinc (ZnSO4) content. The first group: Fe: 20μg / g, Zn: 18μg / g; the second group, the third group and the fourth group Fe: 40,80,160μg / g, Zn were 18μg / g; the fifth group Fe40μg / g, Zn36μg / G. After 20 days of feeding, 65Zn mice were gavaged with a body weight of 5.55 × 10-2GBq / g. Five days’ urine excretion was collected continuously. The zinc absorption, retention and distribution in vivo of each group were determined by 65Zn tracing method. The results showed that there was no significant difference in zinc absorption rate, retention rate and in vivo distribution between groups 1, 2, 3 and 4. Zinc absorption rate in rats in low zinc group (1, 2, 3, 4) There was also a significant difference in the distribution of zinc between the groups 1 and 5, which was significantly higher than that of the high zinc group (group 5). This indicates that the non-heme iron has little effect on the absorption and retention of inorganic zinc in rats under the experimental conditions, while the increase of zinc content in feed can significantly inhibit the absorption and retention rate of zinc, the effect of which is more than that of iron Significant