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奥美拉唑系H~+-K~+-ATP酶抑制剂,在控制卓-艾综合征的高胃酸分泌时,每天服用量达60 mg以上,甚至最高达360 mg。但由于治疗过量可导致长期胃酸缺乏等,为此,本文在试图减少奥美拉唑剂量上进行研究。共有卓-艾综合征患者37人,年龄34~68岁,男/女例数30/7,空腹血清胃泌素水平为124~9510 pg/ml,BAO 35±4mE q/h,MAO 56±4。其中30例为散发的卓-艾综合征,7例为卓-艾综合征伴有多发性内分泌瘤Ⅰ型(MEN-I)。受试者均符合卓-艾综合征的
Omeprazole H ~ + -K ~ + -ATPase inhibitors, in the control of Zhuo - Ai syndrome, high gastric acid secretion, daily intake of 60 mg or more, or even up to 360 mg. However, due to overdose can lead to long-term gastric acid deficiency, and so, this article in trying to reduce the dose of omeprazole study. A total of 37 patients were Zhuo-Ai syndrome, aged 34 to 68 years old, the number of men / women 30/7, fasting serum gastrin levels of 124 to 9510 pg / ml, BAO 35 ± 4mE q / h, MAO 56 ± 4. Among them, 30 cases were exudative Zhuo-Ai syndrome and 7 cases were Zhuo-Ai syndrome with multiple endocrine neoplasia type I (MEN-I). Subjects were consistent with Zhuo - Ai syndrome