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目的 探讨急性缺血性脑卒中患者血浆胱抑素C水平的表达.方法 将112例急性缺血性脑卒中患者设为卒中组,将同期有眩晕症状的89例患者设为对照组,测定两组血浆胱抑素C水平,并进行相关性分析. 结果 卒中组血浆胱抑素C水平显著高于对照组(P<0.01),卒中组大动脉粥样硬化型患者血浆胱抑素C水平显著高于非大动脉粥样硬化型患者(P<0.05),有颈动脉斑块患者胱抑素C水平显著高于无颈动脉斑块患者(t=2.13,P<0.05).性别、高血压、血浆胱抑素C水平与急性缺血性脑卒中的发生有显著相关性(P<0.05).结论 急性缺血性脑卒中患者血浆胱抑素C水平较高,在大动脉粥样硬化型患者和有颈动脉斑块患者体内升高更显著,其可能是缺血性脑卒中发病的危险因素之一.“,”Objective To explore the expression of plasma cystatin C (SCC) in acute ischemic stroke (AIS) patients.Methods A total of 112 AIS patients were assigned to stroke group and 89 ones with vertiginous symptoms to control in the corresponding time period, SCC levels of both groups detected, and correlation analyses performed.Results SCC levels were significantly higher in observation than in control group (P<0.01), so was those in patients with large atherosclerosis (LAS) than in ones with non-LAS (P<0.05) and in ones with carotid artery plaque (CAP) than in ones without (t=2.13, P<0.05) in stroke group.Genders, hypertension and SCC levels were notably related to the development of the AIS (P<0.05).Conclusion SCC levels are higher in AIS patients, especially in ones with LAS or CAP, and which may be one of risk factors of cerebral ischemic stroke.