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VEGF于1983年由Senger等发现 ,分子量34 42KD ,以二巯键连接的糖蛋白二聚体形式存在 ,是一种对热酸稳定的外分泌蛋白 ,可在健康人体多数组织中检出 ,但表达量甚微。人VEGF是一种多功能细胞生长因子 ,可以形成4种不同长度的多肽 ,称为VEGF206、
VEGF was discovered by Senger et al. in 1983 and has a molecular weight of 34 42KD. It exists in the form of a dimeric glycoprotein-linked dimer. It is an exo-secretory protein that is stable to hot acids and can be detected in most healthy human tissues, but expressed. The amount is small. Human VEGF is a multifunctional cell growth factor that can form four different lengths of polypeptide called VEGF206,