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据报告,哮喘病人吸入类固醇能促进支气管纤毛和受损上皮的修复。纤毛形成时,球形的核上纤维颗粒区能形成几个次胞质体,每个次胞质体又形成几个基粒,基粒向细胞边缘游走,与细胞膜相互作用,产生纤毛.中心粒参与纤毛颗粒区的形成.中心粒和基粒上含有类固醇受体。为弄清类固醇对哮喘患者支气管上皮纤毛形成的作用,作者对5例哮喘者分别于口服类固醇治疗前后做了活组织检查,并在透射电子显微镜下进行观察。4例哮喘病人口服强的松龙40mg/d,连续8～12天,1例病人口服甲基强的松龙40mg/d,连续20
It has been reported that asthma inhaled steroids can promote the repair of bronchial cilia and damaged epithelium. Cilia formation, the spherical nuclear fiber zone can form several sub-cytoplasm, each secondary cytoplasm and the formation of a few basal grains, the basal cell migration to the edge of the cell, with the cell membrane interaction, produce cilia .Central Particles participate in the formation of the cilia granulosa region, which contains steroid receptors on the central and basal granules. To understand the role of steroids in bronchial epithelial cilia formation in asthmatic patients, the authors performed biopsies on five asthmatics before and after oral steroid treatment and observed them under transmission electron microscopy. 4 cases of asthma patients oral prednisolone 40mg / d, for 8 to 12 days, 1 patient oral methylprednisolone 40mg / d, continuous 20