Gastrodin blocks neural stem cell differentiation into glial cells mediated by kainic acid

• 作 者: Guifang Sun Zhihao Yuan Boai Z
• 机 构: DepartmentofNeurology,DepartmentofUrology,DepartmentofNeurology
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2012年12期
• 关键词: 神经胶质细胞 神经干细胞 红藻氨酸 细胞分化 天麻素 兴奋性氨基酸 介导 细胞治疗 kainic acid gastrodin neural stem cell
• 基金项目: This study was supported by the National Natural Science Foundation of China. No. 30770758. Acknowledgments： We would like to thank Jinghong Li from the Laboratory of Neurology Department, the First A

Kainic acid can simulate excitatory amino acids in vitro.Neural stem cells,isolated from newborn Wistar rats,were cultured in vitro and exposed to 100-4 000 μM kainic acid for 7 days to induce neuronal cell differentiation,causing the number of astrocytes