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我院从1990年10月至1991年8月共收治8例恶性疟,用氯氨喹啉、伯氨喹啉联合治疗无效,改用蒿甲醚治疗,疗效满意,现报告如下。一、临床资料 8例均为男性,年龄21～47岁,病程4天至2月,病前均到过疫区,皆有发热、溶血性贫血、脾大;3例脑型疟有昏迷、呼吸衰竭。8例在未发作期查血及骨髓片均有恶性疟配子体或环状体。二、治疗方法 8例均曾先用氯伯喹8日疗法无效,改用云南昆明制药厂生产的蒿甲醚。其中2例剂量为80mg,每日1次肌注,
Our hospital from October 1990 to August 1991 were treated 8 cases of falciparum malaria, with chloroquine quinoline, primaquine combination therapy is invalid, use of artemether instead, the effect is satisfactory, are as follows. First, the clinical data of 8 cases were male, aged 21 to 47 years old, duration of 4 days to February, have been infected before the disease, all have fever, hemolytic anemia, splenomegaly; 3 cases of cerebral malaria coma, Respiratory failure. 8 cases of non-episodes of blood and bone marrow tablets have falciparum malaria gametophyte or ring. Second, the treatment of 8 cases were first with chlorine on the 8th ineffective therapy, switch to Yunnan Kunming Pharmaceutical Factory production of artemether. Two cases of dose of 80mg, 1 intramuscular injection daily,