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用IRMA、RRA和RIA等对24例维持血透患者（MHD）测定其血甲状旁腺激素、PTH（l～84）、25（OH）D3、1，25（OH）2D3、BGP、血钙和磷的变化，以探讨它们之间的关系和评估患者骨代谢的状况。MHD患者PTH和BGP升高，透析后则降低；25（（）H）fa和1，25（（）H）。D3降低，透析对其无明显影响；PTH与25（（）H）D3、l，25（（）H）。D3呈负相关，P分别小于0．05和0．01；PTH与BGP呈正相关（P＜0．of）。PTH分泌亢进是骨代谢紊乱的主要因素，MHD患者骨转化率增高。
The levels of parathyroid hormone, PTH (l ~ 84), 25 (OH) D3, 1, 25 (OH) 2D3, BGP and serum calcium were measured by IRMA, RRA and RIA in 24 patients with hemodialysis (MHD) And phosphorus changes to explore the relationship between them and to assess the condition of the patient’s bone metabolism. PTH and BGP increased in patients with MHD and decreased after dialysis; 25 (() H) fa and 1,25 (() H). D3 decreased, no significant effect of dialysis; PTH and 25 (() H) D3, l, 25 (() H). D3 was negatively correlated with P less than 0.05 and 0.01 respectively; PTH was positively correlated with BGP (P <0.of). Hyperosmolar PTH secretion is a major factor in disorders of bone metabolism, MHD patients with increased bone turnover.