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目的对比分析无聚合物紫杉醇涂层支架(垠艺)与可降解聚合物雷帕霉素涂层支架(Excel)治疗冠心病的疗效与安全性。方法选择某院收治的125例冠心病患者,随机分为垠艺组和Excel组,接受PCI治疗。临床随访1年,观察两组支架内有无血栓形成、主要心脏不良事件(MACE)、死亡原因及再次入院情况。结果两组患者均没有发生晚期肯定性支架血栓。共有6例患者死亡,垠艺组2例,Excel组4例。垠艺组的主要心脏不良事件和再次入院率与Excel组的数据近似,差异均没有统计学意义(P﹥0.05)。结论无聚合物紫杉醇涂层支架与可降解聚合物雷帕霉素涂层支架在治疗冠心病及预防心血管疾病作用相当,均有良好的效果。
Objective To compare the efficacy and safety of polymer-free paclitaxel-coated stent (Eyelid) and biodegradable polymer-coated rapamycin-eluting stent (Excel) in the treatment of coronary heart disease. Methods A total of 125 patients with coronary heart disease admitted to a hospital were randomly divided into two groups: Enceral Group and Excel group, receiving PCI. One year after clinical follow-up, the incidence of thrombosis, major adverse cardiac events (MACE), causes of death and re-admission in the two groups were observed. Results There was no advanced definite stent thrombosis in both groups. A total of 6 patients died, two cases of Yin Yi group, Excel group 4 cases. There was no significant difference in the major adverse cardiac events and re-admission rates between the Yin-Yi group and the Excel group (P> 0.05). Conclusion Polymeric paclitaxel-coated stents and biodegradable polymer-coated rapamycin-coated stents have similar effects in the treatment of coronary heart disease and prevention of cardiovascular diseases, all of which have good results.