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患儿,男,17天头部包块进行性增大17天,全身紫斑九天,紫斑先出现在面额及下颌部,一天内迅布全身。入院前三天大便呈柏油状,3~4次/日,少量,便前不哭闹。继之脐部渗血及右鼻孔流血两天后急诊收入我院。病程中不发热。一胎一产,足月顺产,出生体重4 kg,Apgar评分9分。父母非近亲婚配,无遗传病史。其母体健,无服药史及输血史,产前血常规,血小板、出凝血时间均在正常范围。查体:T36.5℃P140次,R44次,反应较差,头顶左侧包块10×10cm、有搏动、无触痛,前囟1×1cm、凹陷,全身皮肤黄染+++、水肿、有大小紫
Children, male, 17 days of head mass progressively increased 17 days, purple body nine days, purple first appeared in the den and the lower jaw, the whole body within a day Xunbu. Three days before admission stool was tarry, 3 to 4 times / day, a small amount, before not crying. Followed by umbilical bleeding and bleeding after the right nostril two days after emergency income in our hospital. No fever during the course of the disease. One fetus was born, term full-term, birth weight 4 kg, Apgar score of 9 points. Parents non-relatives marriage, history of genetic disease. The maternal health, history of non-medication and blood transfusion, prenatal blood, platelets, clotting time are in the normal range. Examination: T36.5 ℃ P140 times, R44 times, the reaction is poor, the head on the left mass 10 × 10cm, with beating, no tenderness, anterior fontanel 1 × 1cm, depression, yellow skin of the body +++, edema , The size of purple