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目的：分析医院住院患者玉类切口清洁手术预防性应用抗菌药物的情况。方法随机抽取我院2013年5月住院患者行玉类切口清洁手术病例60例，了解我院住院患者玉类切口清洁手术如甲状腺切除术、乳腺切除术、疝气修补术等玉类切口抗菌药物预防用药合理性的情况。结果玉类切口清洁手术抗菌药物预防性应用率为33.3%(20例)。不合理情况主要为品种选择不合理10例次，用法与用量不正确9例次，用药时机不合理16例次，用药疗程过长15例次，无溶媒选择不合理及无指征联合用药情况。结论玉类切口清洁手术抗菌药物预防使用存在使用率高、给药时机不合理、疗程过长、抗菌药物选择起点高等问题，提示医院玉类切口清洁手术预防性抗菌药物的应用需要进一步规范化。“,”Objective To analyze the usage of prophylactic antimicrobial agents in hospitalized patients with surgeryⅠ-type incision. Methods 60 cases of hospitalized patients in May 2013 withⅠ-type incision such as thyroidectomy,ade-nomammectomy,and hernia repair were chosen randomly to investigate the rationality of prophylactic use of antibiotics as a prospective study. Results The rate of prophylactic application of antibiotics was 33.3%(20 cases).Of unreasonable cases,improper species selection was 10 times,incorrect usage and dosage was 9 times,improper timing of drug adminis-tration was 16 times,overlong treatment courses was 15 times.There were no problems regarding unsuitable dissolvant selection and drug combination without indication. Conclusion Some problems of prophylactic application of antibiotics still exist,such as higher usage rate,irrational opportunity,longer usage period,higher-ranking drugs and so on,which in-dicates that prophylactic application of antibiotics of cases withⅠ-type incision surgery should be standardized.