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目的探求治疗小儿特发性血小板减少性紫癜的新方法。方法87例11个月～13岁的本科住院患儿随机分为治疗组:57例,对照组:30例,治疗组应用国产人血丙种球蛋白注射液,<2岁300mg/d,3～6岁600mg/d,>7岁600～1200mg/d,肌肉注射,1～2次/d,疗程5～7天。结果治疗组血小板计数达到正常、出血症状消失所需时间较对照组明显缩短(P<0.01)。结论采用肌肉注射给药方法同样能达到静脉输注的疗效,且具有剂量小、费用少、安全性高、不良反应少等优点,尤其值得在基层医院推广使用。
Objective To explore a new method of treating idiopathic thrombocytopenic purpura in children. Methods A total of 87 hospitalized children aged 11 months to 13 years were randomly divided into treatment group (n = 57) and control group (n = 30). The treatment group was treated with domestic human gamma globulin injection (300 mg / d, 6 years old 600mg / d,> 7 years old 600 ~ 1200mg / d, intramuscular injection, 1 ~ 2 times / d, treatment of 5 to 7 days. Results The platelet count of the treatment group was normal, and the time required for the disappearance of bleeding symptoms was significantly shorter than that of the control group (P <0.01). Conclusion The intramuscular injection method can also achieve the effect of intravenous infusion, and has the advantages of small dose, low cost, high safety and less adverse reactions, especially worthy of promotion and use in primary hospitals.