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目的探讨低位直肠癌保肛术与腹会阴联合切除术对病人术后生存和肿瘤复发影响。方法随访1995年1月至2005年6月期间,汕头大学医学院肿瘤医院外科手术治疗286例低位直肠癌,对保肛手术(SPO)与经腹会阴联合切除术(APR)两组病人的临床病理指标、存活率和局部复发状况进行统计学分析。结果保肛手术组160例,术后局部复发率10%,生存期24.4个月,5年存活率为61.6%;经腹会阴切除术(APR)组126例,术后局部复发率13.5%,生存期33.2个月,5年存活率为68.8%,两组存活率比较差异无显著意义(P=0.22),两组术后局部复发率比较差异也无统计学意义(P=0.23)。结论低位直肠癌保肛术与腹会阴联合切除术并不影响低位直肠癌病人术后的生存和肿瘤复发。
Objective To investigate the effect of anal sphincter preservation and abdominal perineal resection on postoperative survival and tumor recurrence in patients with low rectal cancer. METHODS: From January 1995 to June 2005, 286 patients with low rectal cancer underwent surgical treatment at Tumor Hospital, Shantou University Medical College. The clinical data of two groups of patients undergoing anorectal surgery (SPO) and transabdominal perineum combined resection (APR) Pathological indicators, survival and local recurrence were statistically analyzed. Results 160 cases were treated with anorectal surgery, with a local recurrence rate of 10%, a median survival time of 24.4 months and a 5-year survival rate of 61.6%. 126 cases underwent transabdominal perineal resection (APR) Survival of 33.2 months, 5-year survival rate of 68.8%, the survival rate was no significant difference between the two groups (P = 0.22), postoperative local recurrence rate was no significant difference between the two groups (P = 0.23). Conclusion Low rectal cancer anal sphincter and abdominal perineal resection does not affect postoperative survival and tumor recurrence in patients with low rectal cancer.