An expedient one-pot synthesis of highly substituted imidazoles using supported ionic liquid-like ph

• 作 者: Maryam Saffari Jourshari Manouchehr Mamaghani Farhad Shirini Khalil Tabatabaeian Mehdi Rassa Hadiss Langari
• 机 构: Department of Chemistry, Faculty of Sciences, University of Guilan,Department of Biology, Faculty of
• 出 处: Chinese Chemical Letters
• 发表日期: 2013年11期
• 关键词: substituted ionic microbial aldehydes condensation separated ammonium heating ir

An effcient method for the synthesis of imidazole derivatives by a three-component condensation of benzil or 9,10-phenanthrenequinone,aldehydes and ammonium acetate using supported ionic liquidlike phase(SILLP)catalyst under ultrasonic irradiation or classical heating conditions is reported.The present methodology offers several advantages,such as excellent yields,simple procedures,short reaction times,simple work-up and mild conditions.The catalyst is easily separated from the products by fltration and also exhibits remarkable reusable activity.These highly substituted imidazoles were also evaluated for their anti-microbial activity.

An effcient method for the synthesis of imidazole derivatives by a three-component condensation of benzil or 9,10-phenanthrenequinone, aldehydes and ammonium acetate using supported ionic liquidlike phase (SILLP) catalyst under ultrasonic irradiation or classical heating conditions is reported. offers several advantages, such as excellent yields, simple procedures, short reaction times, simple work-up and mild conditions. The catalyst is easily separated from the products by fltration and also exhibits remarkable reusable activity. The highly substituted imidazoles were also evaluated for their anti-microbial activity.