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在同一家庭和相邻社区内,在不长时期内发现遗传性球形红细胞增多症并发一过性造血障碍儿童3例。对早期和恢复期的周围血和骨髓造血作了连续观察,表明有造血细胞左移现象,红系造血抑制,并可见巨形嗜碱性原始红细胞,恢复期有中晚幼红增生。其前驱临床表现、流行性和骨髓变化都符合人类微小病毒B19感染
Three cases of hereditary spherocytosis with transient hematopoietic disorder were found in the same family and adjacent communities within a short period of time. Continuous observation of hematopoiesis in peripheral blood and bone marrow at early and convalescent stages showed that hematopoietic cells migrated to the left and erythroid hematopoiesis was inhibited, and giant basophilic primitive erythrocytes were observed. Its precursor clinical manifestations, epidemiology and bone marrow changes are in line with human parvovirus B19 infection