Synthesis of NAD analogs to develop bioorthogonal redox system

来源 :中国科学：物理学、力学、天文学英文版 | 被引量 : 0次 | 上传用户：dljx1234

【摘要】

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Three new nicotinamide adenine dinucleotide(NAD) analogs were synthesized,and their characteristics as cofactors for Escherichia coli malic enzyme(ME) and its d

【出处】

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中国科学：物理学、力学、天文学英文版

【发表日期】

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2013年3期

【关键词】

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氧化还原系统 NAD 类似物合成烟酰胺腺嘌呤二核苷酸氧化还原反应苹果酸酶辅助因子 NAD analog bioorthogonal oxidore

【基金项目】

：

supported by the National Basic Research Program of China (2012CB721103),,the National Natural Science Foundation of China (21102143)

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Three new nicotinamide adenine dinucleotide(NAD) analogs were synthesized,and their characteristics as cofactors for Escherichia coli malic enzyme(ME) and its double mutant ME L310R/Q401C were analyzed.Each pair of the NAD analog and the double mutant sho

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Synthesis of NAD analogs to develop bioorthogonal redox system

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