Respiratory syncytial virus: the possible trigger of airway remodeling through matrix metalloprotein

• 作 者: WEN Fu-qiang LIU Dai-shun
• 机 构: Department of Respiratory Medicine, West China Hospital, West China School of Medicine, Sichuan Univ
• 出 处: 中华医学杂志（英文版）
• 发表日期: 2007年1期
• 关键词: respiratory syncytial virus matrix metalloproteinase airway remodeling

Respiratory syncytial virus (RSV) is a leading cause of epidemic respiratory tract illness in children. Severe RSV infections involving the lower respiratory tract are primarily seen in young children with naive immune systems and/or genetic predispositions. However, RSV was not recognized as a potentially serious problem in older adults until the 1970s, when outbreaks of the virus infection occurred in long-term care facilities.