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目的研究老年阵发性心房颤动患者采用缬沙坦联合大补元煎加味进行治疗的临床效果。方法 2012年5月至2014年5月120例老年阵发性心房颤动患者,随机分成对照组与研究组,每组60例,两组均进行常规治疗。对照组口服缬沙坦药物,研究组则采用缬沙坦联合大补元煎加味治疗,两组均持续治疗12个月。观察比较两组窦性心律的维持率和临床治疗前后左心房内径的变化情况。结果在临床治疗3个月与6个月之后,两组窦性心律维持率比较差异未见统计学意义(P>0.05);在临床治疗12个月之后,研究组窦性心律维持率降至78.3%,而对照组为58.3%,差异有统计学意义(P<0.05);同时12个月后研究组左心房内径显著小于对照组,差异有统计学意义(P<0.05)。结论对于老年阵发性心房颤动采用缬沙坦联合大补元煎加味进行治疗减少了心房颤动的发作次数,缓解了患者的临床症状,缩短了心房颤动的发作时间,从而提高了老年患者的生活质量,值得在临床上广泛推广应用。
Objective To study the clinical effect of valsartan combined with Dabu Yuan decoction in elderly patients with paroxysmal atrial fibrillation. Methods From May 2012 to May 2014, 120 elderly patients with paroxysmal atrial fibrillation were randomly divided into control group and study group, 60 cases in each group. Both groups were treated routinely. The control group oral valsartan drug, the study group was treated with valsartan combined with Dabu Yuan Jianwei treatment, both groups were treated for 12 months. The maintenance rate of sinus rhythm and the change of left atrial diameter before and after treatment were observed and compared between the two groups. Results After 3 months and 6 months of clinical treatment, there was no significant difference in the maintenance rate of sinus rhythm between the two groups (P> 0.05). After 12 months of clinical treatment, the maintenance rate of sinus rhythm in the study group decreased to 78.3% in the control group, and 58.3% in the control group (P <0.05). At the same time, the diameter of the left atrium of the study group was significantly smaller than that of the control group after 12 months (P <0.05). Conclusion The treatment of elderly patients with paroxysmal atrial fibrillation combined with valsartan combined with Dabu Yuan decoction reduces the number of episodes of atrial fibrillation, alleviates the patient’s clinical symptoms, shortens the onset of atrial fibrillation, thereby increasing the life of elderly patients Quality, it is worth widely in clinical application.