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儿童因为机体发育尚未成熟,药物在体内代谢有其特殊性和复杂性,致使一些药品不适用于12岁以下儿童。在儿科处方中,多年来用药剂量的确定均采用年龄、体重或体表面积来折算。但影响儿童用药剂量的因素是多方面的,儿童的合理用药特别应引起医生、家长的关注。 儿童用药的复杂性主要是由于个体因素所造成。儿童消化系统发育不全、胃排空时间长、消化液分泌少、胃蠕动差等,使药物吸收不规则;儿童肾功能低下,肾血流
Children because of the body is not yet mature, the metabolism of drugs in the body has its own particularity and complexity, resulting in some drugs do not apply to children under 12 years of age. In pediatric prescriptions, the dosage of medication over the years to determine the use of age, weight or body surface area to convert. However, there are many factors that affect children’s dosage. Children’s rational drug use should especially attract the attention of doctors and parents. The complexity of children’s medication is mainly due to individual factors. Children with hypoplasia, gastric emptying a long time, less secretion of digestive juice, poor gastric motility, so that drug absorption irregularities; children with renal dysfunction, renal blood flow