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目的探讨左旋氨氯地平和替米沙坦对老年高血压患者血压变异性(BPV)的影响。方法 90例轻、中度原发高血压病患者分别给予左旋氨氯地平和替米沙坦单药或联合用药,比较治疗前和治疗8周后动态血压和BPV的变化。结果左旋氨氯地平和替米沙坦单药或联合用药8周后患者血压和BPV均有显著降低,以联合用药组下降更为明显。结论不仅能有效地降低老年高血压患者的血压,而且能有效降低BPV,因而是一种理想的联合用药方案,值得推广应用。
Objective To investigate the effects of levamlodipine and telmisartan on blood pressure variability (BPV) in elderly hypertensive patients. Methods Ninety patients with mild to moderate essential hypertension were given single or combined levamlodipine and telmisartan respectively. The changes of ambulatory blood pressure and BPV before and 8 weeks after treatment were compared. Results After treatment with levamlodipine and telmisartan for 8 weeks, the blood pressure and BPV were significantly decreased, especially in combination group. Conclusions not only can effectively reduce the blood pressure in elderly patients with hypertension, but also can effectively reduce BPV, so it is an ideal combination regimen, which is worth popularizing and applying.