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［目的］探讨放疗、化疗、激光治疗等综合治疗措施对阴道癌的疗效及其毒副作用。［方法］1985年8月～1995年7月山东省肿瘤医院收治46例原发性阴道癌患者，全部采用60Co体外照射加腔内后装治疗，12例先以VPC方案化疗两个周期，4例因局部病灶较大，采用YAG激光治疗后行化疗和放疗。［结果］所有病例均随访3年以上，46例病人Ⅱ、Ⅲ期的3年生存率分别为66.7％（4／6）、55.0％（22／40），5年生存率分别为50.0％（3／6）、42.5％（17／40）。放射性外阴炎11例，放射性直肠炎4例，放射性膀胱炎2例，直肠阴道疾1例，未控2例。［结论］中、晚期阴道癌的治疗应采用以放疗为主的综合治疗，只要操作适当，多数患者能取得满意疗效，而且放疗并发症不高。
[Objective] To explore the curative effect and toxicity of radiation, chemotherapy, laser therapy and other comprehensive treatment measures on vaginal cancer. [Methods] From August 1985 to July 1995, 46 cases of primary vaginal cancer were treated in Shandong Tumor Hospital. All of them were treated with 60Co external irradiation and intracavitary after-treatment, and 12 cases were treated with VPC regimen for two cycles. 4 Cases of larger focal lesions, the use of YAG laser treatment after chemotherapy and radiotherapy. [Results] All cases were followed up for more than 3 years. The 3-year survival rates of 46 patients in stage II and III were 66.7% (4/6) and 55.0% (22/40), respectively. The 5-year survival rates were 50.0% 3/6), 42.5% (17/40). 11 cases of radiation vulvitis, 4 cases of radiation proctitis, 2 cases of radiation cystitis, rectovaginal disease in 1 case, 2 cases not controlled. [Conclusion] The treatment of middle and advanced vaginal cancer should be based on radiotherapy - based comprehensive treatment. As long as proper operation, most patients can achieve satisfactory curative effect, and radiotherapy complications are not high.