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通过饲料锌不同含量的摄入，建立了低锌（ＺＤ），过量锌（ＺＥ），及正常锌（ＺＮ）大鼠模型，并检测了大鼠血清、皮层、海马一氧化氮（ＮＯ）含量，以探讨锌与ＮＯ的联系。结果表明ＺＤ、ＺＥ组体ｔ增长值、饲料效价明显低于ＺＮ组（Ｐ＜０．０１）。ＺＤ组血清、海马锌明显低于ＺＮ组，而ＺＥ组则明显高于ＺＮ组。ＮＯ检测显示ＺＤ组血清、海马ＮＯ明显高于ＺＮ组，皮层ＮＯ与ＺＮ组无显著性差异。ＺＥ组血清、皮层ＮＯ非常显著地低于ＺＮ组，海马ＮＯ比ＺＮ组明显增高，但低于ＺＤ组。
Zinc deficiency (ZD), ZE (Zinc deficiency) and normal zinc (ZN) rats were established by feeding different dietary zinc levels. Nitric oxide (NO) contents in serum, cortex and hippocampus , To explore the relationship between zinc and NO. The results showed that the growth value and feed titer of ZD and ZE groups were significantly lower than that of ZN group (P <0.01). Serum and hippocampal ZD in ZD group were significantly lower than those in ZN group, while those in ZE group were significantly higher than those in ZN group. The results of NO showed that NO in serum and hippocampus in ZD group was significantly higher than that in ZN group, but there was no significant difference between NO and ZN in cortex. Serum and cortical NO levels in ZE group were significantly lower than those in ZN group. NO in hippocampus was significantly higher than that in ZN group, but lower than that in ZD group.