论文部分内容阅读
目的观察持续性血液滤过在治疗有机磷农药中毒的疗效及对血清中超敏C反应蛋白(hs-CRP)的影响,以期为指导临床工作提供理论支持。方法收集某院急诊收治的98例患者,随机分为2组,观察组共49例,在常规治疗基础上加用持续性血液滤过治疗,对照组共49例,应用常规治疗。观察2组疗效的差别及治疗后血清中hs-CRP表达的差别。结果观察组的治愈率明显高于对照组,观察组呼吸衰竭和肾功能衰竭的发生率明显低于对照组,观察组意识恢复时间和胆碱酯酶恢复时间均明显短于对照组,观察组治疗后血清中hs-CRP的表达明显低于对照组。结论在常规治疗基础上加用持续性血液滤过,临床效果明显,且能有效下调血清中hs-CRP的表达,临床中可以积极应用。
Objective To observe the curative effect of continuous hemofiltration on the treatment of organophosphorus pesticide poisoning and its influence on serum hs-CRP in order to provide theoretical support for the clinical work. Methods A total of 98 patients admitted to a hospital emergency department were randomly divided into two groups. The observation group consisted of 49 patients. On the basis of conventional therapy, continuous hemofiltration was used. In the control group, 49 patients were treated with conventional therapy. The difference between the two groups was observed and the difference of hs-CRP expression in serum after treatment was observed. Results The cure rate in the observation group was significantly higher than that in the control group. The incidence of respiratory failure and renal failure in the observation group was significantly lower than that in the control group. The recovery time and recovery time of cholinesterase in the observation group were significantly shorter than those in the control group and observation group After treatment, the expression of hs-CRP in serum was significantly lower than that in the control group. Conclusion The addition of continuous hemodilution on the basis of routine therapy has obvious clinical effect and can effectively reduce the expression of hs-CRP in serum, which can be actively used in clinical practice.