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本工作采用裂变径迹技术测定人体血液中的微量铀,血样品直接从健康者、从事铀研究的工作者和白血病患者的手指中取样(20μl),试图确定人体血液中微量铀的统计分布。实验测得健康者血液中微量铀的平均值为(3.06±0.10)×10~(-10)g/ml;从事铀工作者血液中微量铀的平均值为(4.53×0.12)×10~(-10)/ml;而白血病患者血液中微量铀的平均值为(7.74±0.15)×10~(-10)g/ml,是健康者2.5倍。所提供的方法灵敏度高、采血量少,对铀矿工作者职业保护有实用意义,并为寻找理想的解毒和促排药物提供可靠的依据。
This work uses fission track technology to measure trace uranium in human blood. Blood samples are taken directly from the fingers of healthy, uranium workers and leukemia patients (20 μl) in an effort to determine the statistical distribution of trace amounts of uranium in human blood. The mean value of trace uranium in the blood of healthy subjects was (3.06 ± 0.10) × 10 -10 g / ml. The average uranium concentration in uranium workers was (4.53 × 0.12) × 10 ~ -10) / ml; while the average amount of trace uranium in blood leukemia patients was (7.74 ± 0.15) × 10 ~ (-10) g / ml, 2.5 times that of healthy people. The method provided has high sensitivity and less blood collection, which has practical significance for occupational protection of uranium mine workers and provides a reliable basis for finding ideal detoxification and promoting drugs.