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目的:观察艾迪注射液联合顺铂胸腔内注射对晚期肺癌恶性胸腔积液的治疗效果。方法:选取肺癌并恶性胸腔积液患者42例,B超定位胸腔穿刺,尽量抽净胸腔积液,胸腔内注射艾迪注射液50ml及顺铂40mg,每周治疗1次,视胸腔积液量多少连用2次~4次。结果:全组42例中,完全缓解(CR)12例(28.6%),部分缓解(PR)23例(54.8%),无变化(NC)7例(16.7%),总有效率(CR+PR)为83.3%。不良反应轻微,均可耐受。结论:顺铂联合艾迪注射液胸腔内注射治疗恶性胸腔积液为一种安全有效的治疗方法,值得临床推广应用。
Objective: To observe the therapeutic effect of Aidi injection combined with cisplatin intrapleural injection on malignant pleural effusion of advanced lung cancer. Methods: Forty-two patients with lung cancer with malignant pleural effusion were selected. Thoracic puncture was performed by B-mode ultrasonography, pleural effusion was evacuated, 50 ml Aidi injection and 40 mg cisplatin were injected into the thoracic cavity, once a week, depending on the volume of pleural effusion How many used 2 times ~ 4 times. Results: The complete remission (CR) in 12 cases (28.6%), partial remission (PR) in 23 cases (54.8%) and no change (NC) in 7 cases PR) was 83.3%. Minor adverse reactions, can be tolerated. Conclusion: Cisplatin combined with Aidi injection in the treatment of malignant pleural effusion is a safe and effective treatment, which is worthy of clinical application.