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毒性弥漫性甲状腺肿,即Graves病(GD)是甲状腺机能亢进的最常见的致病因素,抗甲状腺药物(ATD)是治疗GD选择较多的手段,但撤药后复发率高,部分患者预后不尽人意。预测ATD治疗GD预后的指标很多,但都不够完善。彩色多普勒超声在预测GD患者经ATD治疗后复发方面有一定价值。如诊断GD时彩色多普勒超声显示甲状腺体积明显增大,平均收缩期峰血流值和体积流量值分别高于139cm/s和195ml/min的患者治疗后复发可能性大。撤药后甲状腺低回声的程度越低,则GD缓解的可能性越大。这些指标均有利于临床医师更好地选择治疗方案并调整治疗周期,使GD患者的药物治疗达到更高的长期缓解率。
Graves’ disease (GD) is the most common causative agent of hyperthyroidism. Antithyroid drugs (ATD) are the most effective treatment for GD. However, the relapse rate is high after the withdrawal of drug and the prognosis of some patients Not satisfactory. There are many indicators for predicting the prognosis of GD with ATD, but they are not perfect enough. Color Doppler ultrasound in the prognosis of patients with GD after ATD recurrence has some value. Such as the diagnosis of GD, color Doppler ultrasound showed significantly increased thyroid volume, the average systolic peak blood flow and volume flow values were higher than 139cm / s and 195ml / min patients after treatment, the possibility of recurrence. The lower the degree of hypoechoic thyroid after withdrawal, the greater the likelihood of GD remission. These indicators are conducive to clinicians to better select the treatment options and adjust the treatment cycle, so that patients with GD drug treatment to achieve a higher long-term response rate.